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Mar

08

New Targets Revealed for Treating Adult Blood Cancer with CRISPR Editing

CDK6 inhibitors/antagonists

New Targets Revealed for Treating Adult Blood Cancer with CRISPR Editing

Adult T-cell leukemia/lymphoma (ATL or ATLL) is a rare type of non-Hodgkin lymphoma that can be found in the blood (leukemia), lymph nodes (lymphoma), skin, or multiple areas of the body. ATLL has been linked to infection with the human T-cell lymphotropic virus type 1 (HTLV-1); however, less than five percent of individuals with HTLV-1 will develop ATLL.

Feb

28

Alcoholism Drug Disulfiram Investigated for Anxiety Disorders

chemokine-pathway

Alcoholism Drug Disulfiram Investigated for Anxiety Disorders

Anxiety disorders are a cluster of mental disorders characterized by significant and uncontrollable feelings of anxiety and fear such that a person's social, occupational, and personal function are significantly impaired. There are several types of anxiety disorders, including generalized anxiety disorder, panic disorder, social anxiety disorder, and various phobia-related disorders. The individual disorder can be diagnosed using the specific and unique symptoms, triggering events, and timing. It is possible for an individual to have more than one anxiety disorder during their life or at the same time and anxiety disorders are marked by a typical persistent course.

Feb

10

Small Molecule Compounds and the VEGF Signaling Pathway

vegf-pathway

Small Molecule Compounds and the VEGF Signaling Pathway

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by fibroblasts that stimulate the formation of blood vessels. Vascular endothelial growth factors are important signaling proteins involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature).

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